the best source of Stem Cells For therapy & treatment:

mesenchymal Adult Stem Cells derived from adipose tissue (fat).
we use Adipose-derived stem cells for therapy at our Stem cell center in Phoenix, Arizona - USA
 
 
A Comparison of 3 Sources of stem cells used in the industry:

 

 

Bone marrow - Only about 50,000 ASCs are said to be harvested at any one time. These mostly become blood cells. Studies have said that mesenchymal stromal stem cells make up only from 1 in 100 to 1 in 10,000 of the total amount present.
Peripheral blood - About 10,000 ASCs could be harvested at any one time. Approximately 50% of these will become blood cells and 50% will become tissue cells.
Adipose tissue (Fat) - We use the adipose stromal source and try to harvest more than 5,000,000 stem cells; studies of adipose have shown that 5% will become blood cells while 95% are mesenchymal stromal stem cells which will become tissue cells.

 

 

Do you offer Bone Marrow Harvesting?

 

We provide only the best source: Adipose Derived Stem Cells....we do not offer Bone Marrow harvested stem cells (see why above).

The method of collecting bone marrow can be very painful and often requires total or spinal anesthesia. In addition, the biggest drawback is the small amount of extracted mesenchymal cells available without expansion.

How long does the procedure take?

Our Stem Cell Center uses a revolutionary new procedure where we extract and reintroduce the stem cells into the patient all within the same day and within the same facility.  There is no culturing done with the autologous cells as we do not wish to change or manipulate the stem cells. They are kept in their natural state until they are reintroduced into the body.  This is in direct contrast to bone marrow extraction and other methods which are used by foreign entities. Since we harvest from the most abundant source of stem cells, located within the patient's own fat-derived samples, we avoid the need to manipulate and multiply these autologous cells, thus helping to ensure their survival.

 What is regenerative medicine?

Regenerative medicine is described as the creation of tissues that can repair, replace, or restore biological structures and/or functions that may be lacking due to congenital defects, aging, disease, or destruction.

What methods are implemented when practicing regenerative medicine?

Doctors have always used a variety of medications and hormones to hinder disease progression and help the body repair itself. Science has shown that balancing hormone levels can optimize the immune system and help to repair diseased or injured tissues. Stem cell therapy is quickly becoming an even more effective tool with which doctors are able to treat many degenerative conditions and activate tissue repair and regeneration.

What is a stem cell?

A stem cell is a term used for a cell that has the potential to replicate and differentiate into a different type of cell. This means that stem cells have the ability to multiply into several different cells and then change into various types of tissues based on several different factors present in their environment. The term stem cell is very broad and there are many different types of stem cells.

When most people hear the term stem cell they think of “embryonic (or fetal) stem cells.” These cells have yet to differentiate and can turn into any type of cell in the body. Because these cells are taken from unborn or unwanted embryos, there has been substantial political and moral controversy surrounding their use. In addition, research outside of the United States has shown that these cells have been associated with the development of tumors (teratomas). We do not use embryonic stem cells.

There is another type of stem cell that is known as an “adult stem cell.” This is a stem cell that is located in different tissues within a person’s body. One of the first places where adult stem cells were discovered was in the bone marrow. Bone marrow primarily contains “hematopoietic stem cells” which have the ability to differentiate into all of the different types of blood cells (red blood cells and white blood cells). A small percentage of bone marrow also contains “mesenchymal stem cells.” These cells come from the mesodermal section of your body and can differentiate into all the different types of tissues. Because such a low number of mesenchymal stem cells are harvested from the bone marrow, they typically have to be cultured (grown for days or weeks) in order to get to a therapeutic level. In contrast, fat (or adipose tissue) is overloaded with mesenchymal stem cells. Estimates put adipose derived mesenchymal stem cells to be at least 500 times more numerous than bone marrow. Because these numbers are so great, there is no need to grow them and they can be used right away.

What are Adult Stem Cells?

Adult Stem Cells are undifferentiated cells that have the ability to replace dying cells and regenerate damaged tissue. These special cells seek out areas of injury, disease and damage where they are capable of rejuvenating healthy cells and enhancing a patient’s natural healing process. Although much is unknown about the details, cutting edge research is beginning to discover the enormous healing potential within these cells. Adult stem cells are being used for a variety of medical treatments to repair and regenerate acute and chronically damaged tissues in humans and animals. The use of stem cells is not FDA approved for the treatment of any specific disease in the United States and the use of these stem cells is entirely investigational. Many reputable international medical clinics have been using stem cell therapy for years to treat a variety of chronic degenerative conditions. These include severe neurologic diseases, eye problems, renal failure, erectile dysfunction, degenerative orthopedic problems, and even cardiac and pulmonary diseases. Adult stem cells appear to be particularly effective at repairing cartilage in degenerated joints and healing damaged eye tissue.

How do adult stem cells heal?

Adult stem cells are known as “progenitor” cells. This means that they have the ability to stay dormant (inactive) in the body for years until some type of injury or disease turns them on. Receptors on the stem cells allow them to migrate to areas that need healing and effect change in that area. Scientists are still unsure if stem cells change into the type of tissue needed for repair or if they simply communicate with existing tissues and initiate healing through an alternative mechanism. Regardless, there are numerous animal and human studies and an enormous amount of scientific evidence that show the amazing reparative potential of these cells.

Do you use embryonic stem cells?

No. Only adult mesenchymal stem cells are used. In addition to current legal limitations, embryonic stem cells are also associated with ethical considerations, tumor formation, and body rejection. Adult stem cells are not associated with any of these potential problems.

What types of diseases and problems can be treated?

The diseases and conditions that can be treated are only limited by the differentiation potential of the stem cells. Because stem cells have migratory function, the exact focal point and mechanism of injury may not even need to be known. There are some conditions where stem cells may not be able to effect change and this can be discussed on a case by case basis. In addition, although the procedure is minimally invasive, each patient needs to be cleared and healthy enough to undergo the treatment. If you would like to talk further, our patient coordinator can go over the potential risks and benefits of the procedure and guide you on making an informed decision on whether the stem cell procedure will be right for you. To receive additional information, you can fill out our initial contact form online or call us at 602-439-0000.

Is our procedure FDA-approved?

NO. However, this procedure does fall under the category of a physician’s right to practice medicine, wherein the physician and patient are free to consider their chosen course of treatment. The FDA does have guidelines about treatment and manipulation of a patient’s own tissues. We are very diligent in our adherence to these guidelines by providing same day treatment and inserting stem cells within the same procedure after less than minimal manipulation.

Why do patients request stem cell treatment?

Patients come to our facility for a variety of different reasons and conditions. Many have been told that they require surgery and are looking for non-invasive options. Others have seen or read compelling testimonials related to stem cell treatment in the literature and on various websites. Our goal is to educate, counsel, and inform patients so that they can make an informed decision about whether stem cell treatment is right for them. We also aim to provide an affordable and quality US alternative to those who have been told that they have to travel overseas for treatment. Most of these trips can cost $20000 to $50000 and we want to offer a quality alternative for a fraction of the cost so that we can provide this potentially life-changing treatment for as many people as possible.

How are the stem cells harvested?

Stem cells are harvested and deployed on the same day. Our patients undergo a minimally-invasive liposuction where fat is drawn out through a cannula and into a closed system. The fat is then transported to our onsite lab for processing. The harvesting procedure generally lasts less than 30 minutes and is done under local anesthesia. Less than 200cc of fat is required and post-operative discomfort and activity restriction is minimal.

Why do you liposuction fat rather than bone marrow as a source of stem cells?

Bone marrow collection can be a very painful procedure and only yields about 50,000 mesenchymal adult stem cells. These cells are then cultured over several days/weeks to arrive at a final count of a few million stem cells prior to injection back into the patient. Recent advances in stem cell science and cutting edge laboratory techniques have made it possible to obtain high numbers of adult stem cells from a person’s own fat. Stem cell counts vary from patient to patient, but we have never had a count under 10 million and average counts are well over 100 million stem cells. This is many times more than could ever be obtained through bone marrow extraction (even after culture).

How do you insure a sterile environment during collection and processing of the stem cells?

Stem cells are harvested using sterile technique and transported to our lab immediately so that they never come into contact with any outside contaminants. This helps to prevent infection as well as contamination of the stem cells.

Why do some stem cell facilities around the world require days or weeks before the mesenchymal stem cells are reinserted back into the patient?

These facilities are obtaining stem cells from bone marrow or blood in relatively small quantities and are then culturing (growing) the cells to create quantities adequate enough to initiate a therapeutic response. Current research seems to indicate that the likelihood of a successful treatment is directly related to the quantity of cells injected. We use adipose derived stem cells that are hundreds or thousands of times more abundant than the levels found in bone marrow so that culturing is not needed. Even after bone marrow culturing, our adipose-derived stem cells will be many times more plentiful than the bone marrow stem cells.

Some stem cell treatment centers make extraordinary claims about their success in the treatment of various problems. Why don’t you?

FDA regulations mandate that no advertising or medical claims can be made and that even website testimonials are prohibited.

Can stem cells treat cancer?

Not at this time. Many people are confused by this because they have heard of cancer patients receiving “stem cell transplants.” This is a completely different procedure than what we are offering. These patients undergo an ablative bone marrow therapy and need stem cells to re-populate their blood and marrow. This is much different from the stem cells that we administer to treat noncancerous human diseases.

Can stem cells cause cancer?

Adult mesenchymal stem cells are not known to cause any type of cancer. You may have heard stories of cancer caused by stem cells, but these are related to the use of embryonic stem cells (Not Adult Mesenchymal Stem Cells). These embryonic tumors are called teratomas and may occur when embryonic stem cells are used.

Can stem cells be used in patients that have (or have had) cancer?

Stem cell therapy is generally thought to be safe for patients with dormant cancers. If someone has had cancer in the past and was successfully treated, there is no reason to withhold stem cell therapy. In most cases, stem cells should not be used in patients with active cancer.

Are there any reports of autologous adipose derived adult mesenchymal stem cells harming any humans or animals?

We are unaware of any cases in the literature where serious harm has resulted from adult mesenchymal stem cell therapy. In addition, we have not had any serious adverse events reported to us as a result of the stem cell treatment that we have performed.

How are the cells administered to the patient?

Depending on the type of treatment required, stem cells are injected or administered into the patient through a variety of different methods. All methods are considered minimally invasive and don’t require surgery of any kind. All of our patients will be given stem cells intravenously in addition to any other methods decided upon by the treating physician. Stem cells that are injected intravenously have receptors on them that allow them to migrate to injured, damaged, or diseased tissue locations and thus potentially provide regenerative healing. In fact, intravenously injected stem cells have been shown to have the capability to cross the “blood-brain barrier” and enter the central nervous system. They can even be identified in the patient’s body many months after deployment.

Can I be expected to improve after stem cell treatment?

Different conditions are treated by different methods and there are varying degrees of success. If the goal is regeneration of joint cartilage, one may not see expected results until several months after treatment. Some patients may not experience significant improvement and others may see dramatic regeneration of damaged tissue or resolution of disease. FDA regulations prevent us from making any sort of claim about expectations for success. However, every patient’s medical information is evaluated individually by a physician and patients are advised on whether or not stem cell therapy may be beneficial for them or if it more appropriate to explore another avenue of treatment.

How long does it take to see improvement?

Stem cell therapy relies on the body’s own regenerative healing to occur. Every patient is different and the regenerative process may take several months before results are seen. In some cases, more immediate responses are possible.

Do you offer this treatment to everyone?

No. All patients need to be medically stable enough to have the treatment in our facility. Some patients may be declined due to the severity of their problem. Other patients may not have conditions appropriate to treat or may not be covered by our treatment.

Are any patients automatically excluded?

Yes. All patients with uncontrolled cancer are excluded. Severely ill patients who may be too sick to travel will also be excluded.

Who decides who is eligible?

The patient coordinator in consultation with the treating physician will make a decision on whether treatment is appropriate based on your medical history, studies, and current research findings.

What are the costs?

Consultations are done on the first day and last about an hour to an hour and a half. The treatment and procedures are done on the day thereafter and take approximately 4-6 hours. Most procedures and treatments only cost $7,100.00 for the entire (1) 1-2 hour consultation (2) harvesting (3) extraction (4) preparation (5) infusion and (6) custom-compounded medication(s). This is a fixed price. The procedure can be done as needed, with possible intermittent therapy as support.