pubmed: erectile dysfunction...
NCBI: db=pubmed; Term=Erectile dysfunction and Stem Cell Therapy
NCBI pubmed
  • Reproductive issues in sickle cell disease.
    Related Articles

    Reproductive issues in sickle cell disease.

    Blood. 2014 Dec 3;

    Authors: Smith-Whitley K

    Abstract
    As medical advances improve survival, reduce disease-related morbidity and improve quality of life, reproductive issues will take higher priority in the sickle cell disease community. A wide variety of topics are captured in this discussion including fertility, gonadal failure, erectile dysfunction and menstrual issues in sickle cell disease. Etiologies of impaired male fertility are multifactorial and include hypogonadism, erectile dysfunction, sperm abnormalities and complications of medical therapies. Much less is known about the prevalence and etiology of infertility in women with sickle cell disease. Reproductive issues in women included in this review are pain and the menstrual cycle, contraception and pre-conception counseling. Finally, long-term therapies for sickle cell disease and their impact on fertility will be presented. Transfusional iron overload and gonadal failure are addressed followed by options for fertility preservation after stem cell transplantation. Focus is placed on hydroxyurea therapy given its benefits and increasing use in SCD. The impact of this agent on spermatogenesis, azoospermia and the developing fetus is discussed.

    PMID: 25472967 [PubMed - as supplied by publisher]

pubmed: erectile dysfunction...
NCBI: db=pubmed; Term=Erectile dysfunction and Stem Cell Treatment
NCBI pubmed
  • Reproductive issues in sickle cell disease.
    Related Articles

    Reproductive issues in sickle cell disease.

    Blood. 2014 Dec 3;

    Authors: Smith-Whitley K

    Abstract
    As medical advances improve survival, reduce disease-related morbidity and improve quality of life, reproductive issues will take higher priority in the sickle cell disease community. A wide variety of topics are captured in this discussion including fertility, gonadal failure, erectile dysfunction and menstrual issues in sickle cell disease. Etiologies of impaired male fertility are multifactorial and include hypogonadism, erectile dysfunction, sperm abnormalities and complications of medical therapies. Much less is known about the prevalence and etiology of infertility in women with sickle cell disease. Reproductive issues in women included in this review are pain and the menstrual cycle, contraception and pre-conception counseling. Finally, long-term therapies for sickle cell disease and their impact on fertility will be presented. Transfusional iron overload and gonadal failure are addressed followed by options for fertility preservation after stem cell transplantation. Focus is placed on hydroxyurea therapy given its benefits and increasing use in SCD. The impact of this agent on spermatogenesis, azoospermia and the developing fetus is discussed.

    PMID: 25472967 [PubMed - as supplied by publisher]